KeyStroke Dynamics - Dangling Issues of Providing Authentication by Recognising User Input

A behavioral biometric such as keystroke dynamics which makes use of the typing cadence of an Individual can be used to strengthen existing security techniques effectively and cheaply. Due to the ballistic (semi-autonomous) nature of the typing behavior it is difficult to impersonate, making it useful as a biometric. Therefore in this paper, we provide a basic background of the behavioural basis behind the use of keystroke dynamics. We also discuss the data acquisition methods, approaches and the performance of the methods used by researchers on standard computer keyboards. In this survey, we find that the use and acceptance of this biometric could be increased by development of standardized databases, assignment of nomenclature for features, development of common data interchange formats, establishment of protocols for evaluating methods, and resolution of privacy issues. Keywords: Authentication, Behavioural biometrics, Identification, keystroke dynamics, typing

Mobile Ad hoc Networks – Dangling issues of optimal path strategy

Ad Hoc network is a collection of wireless mobile hosts forming a  temporary network without the aid of any centralized administration, in which individual nodes cooperate by forwarding packets to each other to allow nodes to communicate beyond direct wireless transmission range. Routing is a process of exchanging information from one station to other stations of the network. Routing protocols of mobile ad-hoc network tend to need different approaches from existing Internet protocols because of dynamic topology, mobile host, distributed environment, less bandwidth, less battery power. The key concern is to analyze the ability of moving nodes in the network using Random Direction Mobility model based on the path availability. Key Words: Mobile ad hoc networks, Routing, Path stabilit

ONE STEP QUANTIFICATION ANALYTICAL METHOD AND CHARACTERIZATION OF VALSARTAN BY LC-MS

Objective: To develop precise LC-MS method for the estimation of valsartan impurities and perform validation as per ICH guidelines.Methods: Valsartan (VLN) and its degradation products were analyzed by reverse phase high-performance liquid chromatography (RP-HPLC) using mobile phase water: acetonitrile: glacial acetic acid: phosphate buffer in the ratio of 500:500:1:0.5 v/v/v/v at 225 nm using column nucleosil C18, 125 ×4.0 mm, 5 µm. VLN sample (VLN SPL) thus obtained an unknown major impurity (UIMP) of 0.5 % at 0.38 retention time ratio (RRt) and purity of VLN was found to be 98.70 % respectively.Results: Estimation of VLN SPL total unknown impurities was found to be 1.3% by RP-HPLC. In similarly by liquid chromatography mass spectroscopy (LC-MS) a typical chromatogram of valsartan (VLN) at Rt 9.03 min and UIMP at Rt 3.3 min were recorded at a total run time of 23 min. Assay of VLN SPL was validated as per international council for harmonization (ICH) guidelines. Average % recovery was found to be 100.04 % for VLN SPL.Conclusion: The proposed work clearly indicates that the method can be easily adapted for the routine one step estimation of VLN active pharmaceutical ingredient (API)

Size at birth and cognitive ability in late life: A systematic review

Recent evidence suggests that growth restriction in utero may lead to neurocognitive disorders in late life, either through impaired brain development or adverse metabolic programming

Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial

Background Most people with stroke in India have no access to organised rehabilitation services. The effectiveness of training family members to provide stroke rehabilitation is uncertain. Our primary objective was to determine whether family-led stroke rehabilitation, initiated in hospital and continued at home, would be superior to usual care in a low-resource setting. Methods The Family-led Rehabilitation after Stroke in India (ATTEND) trial was a prospectively randomised open trial with blinded endpoint done across 14 hospitals in India. Patients aged 18 years or older who had had a stroke within the past month, had residual disability and reasonable expectation of survival, and who had an informal family-nominated caregiver were randomly assigned to intervention or usual care by site coordinators using a secure web-based system with minimisation by site and stroke severity. The family members of participants in the intervention group received additional structured rehabilitation training—including information provision, joint goal setting, carer training, and task-specific training—that was started in hospital and continued at home for up to 2 months. The primary outcome was death or dependency at 6 months, defined by scores 3–6 on the modified Rankin scale (range, 0 [no symptoms] to 6 [death]) as assessed by masked observers. Analyses were by intention to treat. This trial is registered with Clinical Trials Registry-India (CTRI/2013/04/003557), Australian New Zealand Clinical Trials Registry (ACTRN12613000078752), and Universal Trial Number (U1111-1138-6707). Findings Between Jan 13, 2014, and Feb 12, 2016, 1250 patients were randomly assigned to intervention (n=623) or control (n=627) groups. 33 patients were lost to follow-up (14 intervention, 19 control) and five patients withdrew (two intervention, three control). At 6 months, 285 (47%) of 607 patients in the intervention group and 287 (47%) of 605 controls were dead or dependent (odds ratio 0·98, 95% CI 0·78–1·23, p=0·87). 72 (12%) patients in the intervention group and 86 (14%) in the control group died (p=0·27), and we observed no difference in rehospitalisation (89 [14%]patients in the intervention group vs 82 [13%] in the control group; p=0·56). We also found no difference in total non-fatal events (112 events in 82 [13%] intervention patients vs 110 events in 79 [13%] control patients; p=0·80). Interpretation Although task shifting is an attractive solution for health-care sustainability, our results do not support investment in new stroke rehabilitation services that shift tasks to family caregivers, unless new evidence emerges. A future avenue of research should be to investigate the effects of task shifting to health-care assistants or team-based community care

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

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Not AvailableAims: The main objective of the study is to combining the higher yield and micronutrient content along with good grain cooking quality in polished rice. Study Place and Duration of Study: The experiment was conducted in the farm of Indian Institute of Rice Research, Hyderabad, India. The duration of the study was two successive wet seasons 2013 and 2014. Methodology: The experiment was conducted in a randomized complete block design (RCBD). Four rice accessions consist of two parent lines (Samba Mahsuri and Chittimutyalu) and two derivatives (BPCM1 and BPCM2) were grown under normal agronomical conditions, evaluated for their yield, grain quality and nutritional properties. The four genotypes were profiled with RM markers. Results: Both the derivative lines BPCM1 and BPCM2 have shown higher yield advantage (4.5% and 8.8%) than the parent Samba Mahsuri along with quality parameters like amylose content (23.3%, 25%) and gel consistency (21.5, 23.7) as well as high zinc content (20.6 ppm, 24 ppm) moderate iron content (3.6 ppm, 4.3 ppm) in polished rice. High heritability (0.91%) was found for the all traits studied. The association of grain yield is significant with harvest index, test weight and straw yield. Grain zinc content was significantly and positively associated with iron content and negatively associated with total protein. The experiment result indicates that, the micronutrient enhancement could be possible along with grain yield and cooking quality.Not Availabl